Pay in installments of $181.25 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 9 - Aug 14
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
human bcrp vesicle kit hek293Das Human BCRP Vesicle Kit enthlt Inside out Membranvesikel aus HEK293 Zellen, die transient das Breast Cancer Resistance Protein (BCRP ABCG2) berexprimieren. Das Kit ermglicht ATP abhngige Substrattransportstudien im High Throughput Format und ist konform mit den FDA (2017) und EMA (2013) Leitlinien zur Charakterisierung von Arzneimittelwechselwirkungen (DDI). Hergestellt von Cell4Pharma. Exklusiv im DACH Raum erhltlich ber SeamlessBio. Transporter
Das Human BCRP Vesicle Kit enthält Inside-out-Membranvesikel aus HEK293-Zellen, die transient das Breast Cancer Resistance Protein (BCRP / ABCG2) überexprimieren. Das Kit ermöglicht ATP abhängige Substrattransportstudien im High-Throughput-Format und ist konform mit den FDA (2017)- und EMA (2013)-Leitlinien zur Charakterisierung von Arzneimittelwechselwirkungen (DDI).
Hergestellt von Cell4Pharma. Exklusiv im DACH-Raum erhältlich über SeamlessBio.
Transporter-Profil
Name: BCRP, Breast Cancer Resistance Protein, ABCG2, ATP-bindende Kassette Unterfamilie G Mitglied 2
Gen: ABCG2
ATP/AMP-Ratio: >10 (garantiert)
Gewebsexpression: Plazenta, Stammzellen, Prostata, Dünndarm, Gehirn, Dickdarm, Leber, Brustdrüse, Niere
Bekannte Substrate: Estron-3-Sulfat (E1S), Methotrexat, Irinotecan, Pantoprazol, Rosuvastatin, Topotecan, Chlorothiazid, Mitoxantron, SN-38, Glibenclamid
Kit-Inhalt (100 Reaktionen)
- Vesikel-Vial (100 Reaktionen), BCRP-überexprimierende
- HEK293-abgeleitete Vesikel
- AMP-ATP-Lösung (100 mM), Cell4Pharma
- Assay-Puffer, Cell4Pharma
Anwendungen
- Identifikation von Efflux-Transporter-Substraten
- Drug-Drug-Interaction-(DDI)-Studien gemäß FDA/EMA-Leitlinien
- Inhibitionsstudien (IC50-Bestimmung)
- High-Throughput-Screening (Radiolabel-, Fluoreszenz-, LC-MS-Detektion)
Regulatorische Konformität
Der vesikuläre Transportassay mit BCRP-Vesikeln wird im FDA Drug
Interaction Guidance (2017) und in der EMA-Leitlinie zur Untersuchung von
Arzneimittelinteraktionen (2013) für die Charakterisierung
transporter-vermittelter DDI in der Arzneimittelentwicklung empfohlen.
Technische Spezifikationen
Wirtszelle: HEK293 (humane embryonale Nierenzelle)
Vesikeltyp: Inside-out-Membranvesikel
Format: 100 Reaktionen pro Kit
Detektion: Radiolabel / Fluoreszenz / LC-MS kompatibel
Lagerung: –80 °C
Verwandte Produkte
- Human Control Vesicle Kit (C4PVK009) – empfohlen als Negativkontrolle in BCRP-Transportassays
- Human Pgp Vesicle Kit (C4PVK010) – für parallele P-gp-Efflux-Messung
- ciPTEC-OAT1 Assay-Ready Cells – für zellbasierte Nephrotoxizitäts- und Transporterstudien
- Human Serum AB Male OTC (SeamlessBio) – zur Supplementierung von ciPTEC-Kulturmedien
Alle Produkte auf Anfrage.
Kontakt: [email protected] | Telefon: +49 851 37932226
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.2 ★★★★★
Based on 18 reviews
Sort
Product Reviews
★★★★★ 5
Good trash bags but would like this sent in 30 gallons at not a huge price
Style: Citrus Spritz
Even though I thought I bought 30 gallon not 13 gallon I still like the product . We used a couple of rhe bags . It worked out some9ne else needed this size so we just sold it to another and I have to reorder NY size downfall I guess they don't make 30 gallon in this scent that part I'm sad about its the one scent that doesn't bother my senses like the others do.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 16, 2026
★★★★★ 5
Durable and Smells Nice
Style: Lavender Vanilla Bliss
Durable, stretchable and they smell nice.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 25, 2026
★★★★★ 5
Strong
Style: Citrus Spritz
What can i say? Strong trash bags.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 27, 2026
★★★★★ 3
Good, could be better.
Style: Fresh Clean Breeze-Black
Nice scent, but not as "heafty" as they used to be. They break a lot more easily.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 18, 2026
★★★★★ 5
Dogs love them!
Color: 3 Colors
Dogs love them! Larger than your average tennis balls, satisfying for my dogs to chew on, the squeak isn't too annoying, colorful enough I can find them in the bushes.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 28, 2026