SKU: 92256499174

Co-Lokus Cocoa Braun (Französische Bulldogge)

Sale price$44.10 Regular price$49.00
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Description

Co-Lokus Cocoa Braun (Französische Bulldogge)Braune oder schokoladenfarbene Fellfarbe ist in vielen Hunderassen aufgrund von Varianten am B Lokus auf dem TYRP1 Gen hufig. Beim Franzsischen Bulldoggen wurden zwei Varianten in zwei verschiedenen Genen (TYRP1 und HPS3) mit brauner Fellfarbe in Verbindung gebracht. Es gibt subtile, aber deutliche Unterschiede in Fell , Haut und Augenfarbe zwischen TYRP1 und HPS3 homozygoten Hunden. Hunde mit zwei Kopien der HPS3 Mutation haben eine etwas dunklere

Braune oder schokoladenfarbene Fellfarbe ist in vielen Hunderassen aufgrund von Varianten am B-Lokus auf dem TYRP1-Gen häufig. Beim Französischen Bulldoggen wurden zwei Varianten in zwei verschiedenen Genen (TYRP1 und HPS3) mit brauner Fellfarbe in Verbindung gebracht. Es gibt subtile, aber deutliche Unterschiede in Fell-, Haut- und Augenfarbe zwischen TYRP1- und HPS3-homozygoten Hunden. Hunde mit zwei Kopien der HPS3-Mutation haben eine etwas dunklere Fellfarbe und hellere Augen als die TYRP1-bezogenen braunen Hunde. Die mit dem HPS3-Gen verbundene braune Fellfarbe bei Französischen Bulldoggen wurde als Cocoa bezeichnet. Cocoa erscheint bei erwachsenen Hunden etwas dunkler als bei jungen Hunden.

Verschiedene Forschungen zeigen, dass die meisten braunen Französischen Bulldoggen auf Varianten im HPS3-Gen und/oder TYRP1-Gen zurückzuführen sind. Die Ergebnisse einer Forschungsgruppe und Testdaten in unserem Labor legen nahe, dass eine kleine Anzahl brauner Französischer Bulldoggen keine der kausalen Varianten besitzt. Wir erwarten daher, dass es einige andere, noch nicht charakterisierte kausale Varianten gibt, die braune Farbe bei Französischen Bulldoggen verursachen können.

N/N

Variante für Cocoa ist nicht vorhanden. Der Hund wird immer das 'N'-Allel an jeden potenziellen Nachwuchs weitergeben.

CO/N

Der Hund trägt eine Kopie des 'Cocoa'-Allels und eine Kopie des 'N'-Allels. Es besteht eine 50%ige Wahrscheinlichkeit, das 'Cocoa'-Allel an den Nachwuchs weiterzugeben.

CO/CO

Der Hund trägt zwei Kopien des 'Cocoa'-Allels und wird die Cocoa-Fellfarbe ausdrücken. Der Hund wird ein rezessives 'Cocoa'-Allel an seinen gesamten Nachwuchs weitergeben.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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SKU: 92256499174

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4.8 ★★★★★
Based on 16 reviews
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Verified Purchase
Fabric Crazy
Fort Morgan, US
★★★★★ 5
Really nice shoes
Size: 9, Color: Black Polished Full Grain
My husband enjoys wearing these shoes. Very classy looking. They fit well. They arrived quickly. He liked them so much he ordered another pair in a different color which have worked out just as well.
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Reviewed in the United States on February 3, 2026
T
Verified Purchase
the agitator
Los Angeles, US
★★★★★ 4
Penny Loafer
Size: 11 Wide, Color: Burgundy Polished Full Grain
I am ending them bak and will order the sae shoe at size 10 1/2. Most shos I fit are 11 however these were too large. They are a beautiful shoe! I will ofder a 10 1/2
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Reviewed in the United States on January 13, 2025
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Verified Purchase
Hugh62
Charlottesville, US
★★★★★ 1
Poor quality control - maybe outlet store leftovers
Size: 11.5, Color: Burgundy Polished Full Grain
The two shoes were not the same size. They were both labeled 11 1/2 but one shoe was larger than the other and the fit was poor. I returned the first pair and ordered a replacement. This time the shoes were close to the same size but too loose and the left one has sewing issues. I've bought Johnston & Murphy for years because of the quality. These were to replace an existing pair of burgundy penny loafers that have finally worn out (even after several heal/sole replacements). That is the expected quality. I suspect Nashville Shoe Warehouse may be handling shoes that didn't measure up for the quality; more like an outlet mall than getting the J&M quality I've come to expect. Update: went to Johnston & Murphy site to buy "direct" from the manufacturer. There were several recent reviews where the shoes were long and didn't fit properly. Genesco - please step up the manufacture / crafting of these classic shoes to the level of quality they used to have.
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Reviewed in the United States on July 21, 2025
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Verified Purchase
BetterEveryDay
Pawtucket, US
★★★★★ 5
I usually wear 11.5's, but I buy 1/2 size smaller to accommodate for stretch. Leather relaxes.
Size: 11, Color: Burgundy Polished Full Grain
5 STARS: These shoes are awesome. I keep coming back for more. I have major foot problems, have tried all kinds of shoes, orthotics, and inserts... but believe it or not, these shoes work better than any of that stuff. I wear them daily. I buy lots of them, for home, for church, and I'm getting my first pair of J&M boots today, for winters in Indiana... Brrrr
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Reviewed in the United States on December 18, 2025
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Verified Purchase
tjw
Chelsea, US
★★★★★ 3
Way too narrow
Size: 9.5 Wide, Color: Burgundy Polished Full Grain
I ordered a wide in this shoe, but it was still way too narrow. I had to return them. Otherwise, it looked like a nice quality shoe.
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Reviewed in the United States on February 12, 2026

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