SKU: 70960147026

CD117/c-Kit Fc Chimera Protein, Mouse

Sale price$124.20 Regular price$138.00
Save 10%

Pay in installments of $34.50 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 22 - Jul 27

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

CD117/c-Kit Fc Chimera Protein, MouseProduct Specification Species Mouse Synonyms CD117 antigen; CD117; ckit; c kit; EC 2. 7. 10; EC 2. 7. 10. 1; KIT; PBT; piebald trait; Proto oncogene c Kit; proto oncogene tyrosine protein kinase Kit; SCF R; SCFR; SCFRmast stem cell growth factor receptor; soluble KIT variant 1; Tyrosine protein kinase Kit; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein Accession P05532

Product Specification


Species Mouse
Synonyms CD117 antigen; CD117; ckit; c-kit; EC 2.7.10; EC 2.7.10.1; KIT; PBT; piebald trait; Proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; SCF R; SCFR; SCFRmast/stem cell growth factor receptor; soluble KIT variant 1; Tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Accession P05532-2
Amino Acid Sequence Ser25-Pro523, with C-terminal His
Expression System HEK293
Molecular Weight 95-120kDa (Reducing)
Purity >95% by SDS-PAGE & >95% by SEC-HPLC
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized Powder
Storage Buffer PBS, PH7.4, 5% trehalose
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference


1.Kimura, Y. et al. (2011) PLoS ONE 6:e26918. 2.Tallini, Y.N. et al. (2009) Proc. Natl. Acad. Sci. USA 106:1808. 3.Bashamboo, A. et al. (2006) J. Cell Sci. 119:3039. 4.Sun, L. et al. (2004) J. Clin. Invest. 113:1364.

Background

Stem Cell Factor Receptor (SCF R), also known as c-Kit and CD117, is a widely expressed 145 kDa receptor tyrosine kinase. It is the cellular homolog of the feline sarcoma virus protein, v-Kit. Binding of SCF R to SCF, also known as Steel Factor and Kit Ligand, promotes the survival, differentiation, and mobilization of progenitor cells in multiple lineages. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 70960147026

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.5 ★★★★★
Based on 23 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
C
Verified Purchase
Cathy May
Whiting, US
★★★★★ 5
Excellent Product!
Scent: Vanilla
This is amazing. Very light feeling on the skin, smells great, and the shimmer is very subtle.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 2, 2026
T
Verified Purchase
Theresa Marie
Alexandria, US
★★★★★ 5
I absolutely love the Saltair line of products!
Scent: Sandalwood
I used the body wash at a friend's house and fell in love, especially with the Santal Bloom scent! This body oil is just so amazing and feels so silky and soft. It's especially effective if you use it right out of the shower. It adds a beautiful glow and I even use a little in my hair. It's quite concentrated so a little goes a long way. I have even mixed it into my favorite coconut oil and it mixes beautifully. Don't sleep on this line!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 1, 2026
L
Verified Purchase
Lauren
Lowell, US
★★★★★ 5
Smells great
Scent: Golden Hour
Love this, my favorite scent from this line. Very subtle glitter so I still feel age appropriate. It’s an oil soy skin does feel oily for a little bit afterwards until it soaks in. It has lasted me quite awhile so I do feel it’s good value for the money. Have reordered a few times.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 6, 2026
A
Verified Purchase
Amazon Customer
Grantham, US
★★★★★ 4
Great Glow and Scent, But Fades Quickly and Runs Out Fast
Scent: Vanilla
The Saltair Shimmering Body Oil in Salt Water Vanilla is a beautiful product. The only 3 reasons I don’t give it 5 stars are because: 1. The shimmer is not very long-lasting. When I apply it before bed, most of the shimmer effect is completely gone and absorbed by my sheets by the morning. I assume pants and leggings would absorb it in the same way, but I’ve only ever worn shorts after applications during the day, and even then, the shimmer seems to fade after 4–6 hours. 2. I have to apply a lot of oil to achieve the amount of shimmer I desire. It averages about 20–25 pumps per use. 3. The 4-ounce bottle size, combined with needing a lot of product for each application, means I’m going to run out of it pretty quickly. Here’s why I like this product: 1. The glow: If you’re looking for a subtle glow and a light shimmer effect, this oil is perfect for you; apply it before a night out, while wearing a swimsuit, or when going to the gym in your favorite workout set for a beautiful gleam. 2. The scent: It’s a divine, warm mix of sweet and spicy notes. It smells like vanilla, amber, and toasted marshmallow. It pairs really nicely with tropical, woodsy, sweet, or spicy perfumes—it’s very versatile. 3. Consistency and absorption: The oil absorbs nicely and has a light, runny consistency. Because it’s a dry oil, it isn’t too thick, nor does it leave a sticky feeling on the skin. 4. How my skin feels: I’ve used this oil 4 nights in a row, and every single morning I wake up, my skin feels so soft and smooth, with no residual stickiness or residue left behind.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 5, 2026
M
Verified Purchase
marymac
Louisville, US
★★★★★ 5
Saltair shimmer
Scent: Sandalwood
Nice on the body. Easy to apply. I use it with my lotion for an all over glowy shimmer. It will be very nice in the summer. Nice scent, no irritation.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 15, 2026

recommand products