SKU: 19773956515

Core Nutritionals 5-AT

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Description

Core Nutritionals 5-AT5 Etioallocholen 3b,7b,17b triol: More commonly known as androstenetriol, 5 etioallocholen 3 beta 7 beta 17beta triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex

5-Etioallocholen-3b,7b,17b-triol: More commonly known as androstenetriol, 5-etioallocholen-3 beta-7 beta-17beta-triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!

Though DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).

Like DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.

In less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:

1. Preventing our muscle cells from uptaking glucose (inducing insulin resistance).
2. Preventing muscle protein synthesis.
3. The breakdown of glycogen (the compound responsible for that “full look”).
4. Suppressing the immune processes involved in muscle growth.

While these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.

Enter DHEA and its metabolite, androstenetriol: In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. In fact, androstenetriol is one of the most potent anti-glucocorticoids the body produces – exerting almost unbelievable effects in certain pro-inflammatory cell lines.

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SKU: 19773956515

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4.3 ★★★★★
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G. Corder
Carnegie, US
★★★★★ 5
Fun for reading over FaceTime
Format: Board book
This is an adorable book! It’s so much fun to read with kids. My grandson loves it! I got it for him when he was 9 months old and he still loves it at almost 2. Kids love the suspense of seeing what animal the zoo sent next and opening the flap to see. The pictures are cute and colorful and the writing is just right to keep little ones interested. I live across the country from my grandson, but my daughter is good about FaceTiming. So I use that time to read to him. And this book is great for that. He loves when the flaps open to see what animal is there. (Although he already knows, because we’ve read it so many times.) But we love it anyway. It’s a wonderful book. Definitely worth buying.
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Reviewed in the United States on March 15, 2026
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A. Manzur
Chelsea, US
★★★★★ 5
Great book
Format: Board book
Lovely book! very engaging! kids love the flaps and they're big and easy to pull up for little hands. Helps build vocabulary
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Reviewed in the United States on February 13, 2026
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Amber R
Battle Creek, US
★★★★★ 5
2 year olds favorite
Format: Board book
This is my 2 year olds favorite book. We had to get him the rest of the authors books and this is his favorite. Highly recommended!
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Reviewed in the United States on April 25, 2026
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Raju
Charlottesville, US
★★★★★ 5
A Fun, Repetitive Book That Keeps Kids Engaged
Format: Board book
Dear Zoo has become a go-to read during playtime because the lift-the-flap feature keeps my baby actively involved. The simple storyline and repetition make it easy for young children to follow and anticipate what’s coming next. Pros: Lift-the-flap design encourages interaction and curiosity Repetitive text helps with early language development Short and engaging—great for babies and toddlers Sturdy board book holds up well Cons: Flaps can bend if handled roughly Very simple story, so older toddlers may outgrow it Conclusion: Dear Zoois a classic interactive book that works especially well for younger children.
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Reviewed in the United States on December 13, 2025
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Nina C.
Port Orchard, US
★★★★★ 5
Perfect for little ones
Format: Board book
This was perfect for my 4 yeara olds birthday. He reads it twice a week and loves lifting the flaps and making the animal noises.
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Reviewed in the United States on April 1, 2026

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