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Description
Biotinylated LILRB3/CD85a/LIT5 Fc&Avi Tag Protein, HumanProduct Specification Species Human Synonyms LILRB3, CD85a, ILT5 Accession O75022 Amino Acid Sequence Gly24 Glu443, with C terminal human IgG1 Fc&Avi tag
Product Specification
| Species | Human |
| Synonyms | LILRB3, CD85a, ILT5 |
| Accession | O75022 |
| Amino Acid Sequence | Gly24-Glu443, with C-terminal human IgG1 Fc&Avi tag GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 85-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Human Fc Tag, Avi Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Kang X. et al. (2016) Inhibitory leukocyte immunoglobulin-like receptors: Immune checkpoint proteins and tumor sustaining factors. Cell Cycle. 15(1): 25-40. |
Background
LILRB3 is a member of LILRB family that is restrictively expressed on myeloid cells, including monocytes, neutrophils, eosinophils, and basophils (as well as on in vitro differentiated mast cells and osteoclasts). LILRB3 contains four cytoplasmic ITIM motifs hat may contribute to negative regulation of immune response. Ligation of LILRB3 in human myeloid cells led to inhibition of immune activation. LILRB3 may be an inhibitor of allergic inflammation and autoimmunity. However, the ligand for LILRB3 has not been identified, and the downstream signaling of LILRB3 is unclear. It is noteworthy that LILRBs, including LILRB3, are primate specific.
LILRB3 is also expressed on some myeloid leukemia, B lymphoid leukemia, and myeloma cells. It is reportedly co-expressed with stem cell marker CD34 and with myeloma marker CD138.
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4.0 ★★★★★
Based on 7 reviews
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Product Reviews
★★★★★ 4
Cute and Comfy
Size: 8.5, Color: Brown
This shoe is cute. It is nice and comfy, but it is NOT brown. A caramel, maybe a tan, but NOT the color brown we see with the description. Not a chocolate brown as it appears or looks to be on the amazon post. It is NOT the deep description color that it shows to be. It is not. It is comfortable. It fors fit exact and it is still cute.
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Reviewed in the United States on April 13, 2021
★★★★★ 5
Beautiful heeled mule
Size: 7, Color: White
Great heeled mule. The fir is a little small/slim. And I do not have a wide foot. But they still fit and they are beautiful and go with anything spring and summer!!
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Reviewed in the United States on May 27, 2021
★★★★★ 3
Cute but overpriced
Size: 7, Color: Black
The shoe is cute but I would not purchase again because extremely overpriced! Cheaply made but comfortable. I have only tried them on in the house so I can’t rate wearing them for an extended period of time.
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Reviewed in the United States on May 29, 2026
★★★★★ 5
Nice Shoe
Size: 5.5, Color: Black
I don't usually buy shoes online because you don't know about the comfort of the shoe, but I was pleasantly surprised with this shoe. Comfort is really good and the quality and style were just what I was looking for. So happy with this purchase. Shoe was also delivered as promised.
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Reviewed in the United States on April 24, 2022
★★★★★ 1
One size too small
Size: 8.5, Color: Black
These run at least one size small. The sole is slick also. Order up for sure.
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Reviewed in the United States on January 30, 2022