SKU: 42034761994

TIMP-1 Protein, Mouse

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Description

TIMP-1 Protein, MouseProduct Specification Species Mouse Synonyms TIMP1, CLGI, TIMP Accession P12032 Amino Acid Sequence Cys25 Arg205, with C terminal His Tag Expression System HEK293 Molecular Weight 25 30kDa (Reducing) Purity 95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation. Stability &

Product Specification


Species Mouse
Synonyms TIMP1, CLGI, TIMP
Accession P12032
Amino Acid Sequence Cys25-Arg205, with C-terminal His Tag
Expression System HEK293
Molecular Weight

25-30kDa (Reducing)
Purity ＞95% by SDS-PAGE and HPLC.
Endotoxin <0.1EU/μg
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Hornebeck W. (2004) Down-regulation of tissue inhibitor of matrix metalloprotease-1 (TIMP-1) in aged human skin contributes to matrix degradation and impaired cell growth and survival. Pathol Biol. 51(10): 569-573.
2、Soini Y. et al. (2001) Expression of MMP2, MMP9, MT1-MMP, TIMP-1, and TIMP2 mRNA in valvular lesions of the heart. J Pathol. 194(2): 225-231.

Background

TIMP metallopeptidase inhibitor 1 is also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. TIMP1 is a glycoprotein with a molecular mass of 28 kDa produced by a wide range of cell types. Tissue inhibitor matrix metalloproteinase 1 (TIMP1), which belongs to TIMP gene family, is a natural inhibitor of the matrix metalloproteinases (MMPs). Tissue inhibitor of metalloproteinases 1 (TIMP1) was the secreted factor with the strongest male-biased expression in patient-derived pancreatic tumors. Male-specific up-regulation of systemic TIMP1 was demonstrated in PC mouse models and patients.

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SKU: 42034761994

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4.8 ★★★★★
Based on 886 reviews
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Ringo
Birmingham, US
★★★★★ 5
A Baby Boomer dream come true!
Format: Hardcover
I love the Golden Age omnibus Batman series. However, for many of us baby boomers the Silver Age is what we’ve been craving. Those were exciting days back then, looking for the new issue of Batman or Detective Comics on the newsstand. One of the previous reviewers is correct, though, there are some missing issues between the last golden age omnibus and this, the first silver age omnibus, that need to be put into book form at some point. I certainly hope we get them. But more than anything I am really hoping that this will not be the first and last silver age omnibus. By my count, there are almost exactly the issues needed to make three more silver age volumes before we get to the “new look Batman,” which started in mid 1964. And frankly, I hope they continue on with a “new look” omnibus series as well. This first volume, though, was absolutely beautiful! The re-creation of these old panels is breathtaking. When you go back and look at the old dot matrix original issues and compare them to the re-printings contained within this omnibus…well…there simply is no comparison. Batman, the Silver Age Omnibus Volume One is practically as good as it gets. The only thing more I could have wished for would have been the inclusion of the old advertisements that decorated the pages of the original issues. Other than that, this book is perfect. Wow!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 27, 2022
A
Verified Purchase
Amazon Customer
Alexandria, US
★★★★★ 5
Quality Reproduction of Artwork
Format: Hardcover
The book looks great and includes a massive amount of content; however, this is DC Batman Silver Age stories verses Marvel Silver Age stories. It was hard getting through some of the stories and did not make it through the entire book. I think I would have enjoyed the stories that came before this collection and/or the great Neal Adams Batman content. This era of batman stories was just silly and boring. But just my opinion.
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Reviewed in the United States on November 5, 2024
M
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Morgan Painter
Birmingham, US
★★★★★ 5
Terrific buy for old time Batman comics.
Format: Hardcover
These Batman Omnibus collections are great for compiling these still amazing comics in an inexpensive way. Much cheaper than trying to get the original comics.
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Reviewed in the United States on August 8, 2025
D
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Derek Allen
Massapequa, US
★★★★★ 4
This era of Batman is well-written and beautifully drawn
Format: Hardcover
This era of Batman is well-written and beautifully drawn. But that consistency is also its weakness. These are mostly detective stories, hardly any super villains, mostly gangsters and corrupt businessman. Batwoman is introduced here, and Bat-hound is featured in certain stories. Even Superman and the Joker appear briefly. Someone commits a crime, Batman figures out who did it, and the story ends in 12 pages. The Batman team was a well-oiled machine in the 1950s Still I recommend it. Worth it for the art alone and some great novelty stories.
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Reviewed in the United States on December 27, 2025
B
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Bat Brain
Draper, US
★★★★★ 5
Good for depression.
Format: Hardcover, Format: Hardcover
A lot of modern day comics have a drab flat look to them, the tales are typically high stakes crossover events that require lots of in depth reading with low pay off. These take me back to a less complicated time, without being constantly reminded of how dire the world is today. This book is full of fun one off events, that keep you hooked. Also, while I enjoy a lone brooding Batman, I am also a big fan of friendly easy going Batman and Robin, Robin is the reader inserted, asking all the right questions. All in all this book is worth every penny, and I look forward to sharing it with future generations.
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Reviewed in the United States on October 18, 2023

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