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Description
Growth hormone Protein, HumanProduct Specification Species Human Synonyms Growth hormone; GH1; Somatotropin; Growth hormone; GH; GH N; Growth hormone 1 Accession P01241 Amino Acid Sequence Phe27 Phe217 Expression System E. coli Molecular Weight 20 23kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 2EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 500mM NaCl, pH8. 0 Reconstitution Reconstitute at 0. 1 1 mg ml according to
Product Specification
| Species | Human |
| Synonyms | Growth hormone;GH1;Somatotropin;Growth hormone;GH;GH-N;Growth hormone 1 |
| Accession | P01241 |
| Amino Acid Sequence | Phe27-Phe217 |
| Expression System | E.coli |
| Molecular Weight | 20-23kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.2EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM Tris, 500mM NaCl, pH8.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is a peptide hormone that stimulates growth, cell reproduction and regeneration in humans and other animals. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) as well as by signals from the periphery-ghrelin and leptin. The human GH cDNA encodes a 217 amino acid (aa.) residue precursor protein with a 26 aa. putative signal peptide. By alternative splicing, at least four isoforms of GH have been identified.
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