SKU: 79098324881

Human L1CAM/CD171 Protein, His tag

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Description

Human L1CAM/CD171 Protein, His tagProduct Specification Species Human Synonyms Neural cell adhesion molecule L1, N CAM L1, NCAM L1, CAML1, MIC5 Accession P32004 Amino Acid Sequence Protein sequence (P32004, Ile20 Glu1120, with C His tag)

Product Specification


Species Human
Synonyms Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CAML1, MIC5
Accession P32004
Amino Acid Sequence

Protein sequence (P32004, Ile20-Glu1120, with C-His tag) IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATE

Expression System HEK293
Molecular Weight Predicted MW: 124.9 kDa Observed MW: 130, 180 kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag with C-His tag
Physical Appearance Lyophilized Powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Neural cell adhesion molecule L1, also known as L1CAM, is a crucial glycoprotein in the nervous system. It belongs to the immunoglobulin superfamily of cell adhesion molecules. L1 plays a vital role in various neural processes, including neuronal migration, axonal outgrowth, and synapse formation. It mediates cell - cell adhesion through homophilic and heterophilic interactions, which are essential for the proper development and function of the nervous system. Mutations in the L1CAM gene can lead to several neurological disorders, such as X - linked hydrocephalus, mental retardation, and spastic paraplegia, highlighting its significance in maintaining normal neural function.

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SKU: 79098324881

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Reviewed in the United States on January 30, 2015
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★★★★★ 4
Hydrating
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Waukegan, US
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My 75 year old hands appear softer and younger!
Avene Cicalfate Restorative Hand cream leaves my hands feeling very soft! A little goes a long way, I have had mine for a year. Soon I will be purchasing another tube. Yes, it is a little pricey for a hand cream, but does the job better then any other product I have used on my hands. Highly recommend this hand cream if you have dry, sensitive skin. It also has no added fragrance which I really appreciate!
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Reviewed in the United States on June 4, 2025
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Olga
Waukegan, US
★★★★★ 5
Excellent product at a very good price. I will buy it again.
This is an excellent product at a fair price. The cream creates a barrier that protects the skin, while mosturizes it. leaves hands very soft, and it doesn't feel greasy. I know that this is a favorite brand (Avene) in France, and Amazon offers it at a very good price. I will buy it again, from Amazon. I bought it this year in Paris, and it was more expensive there.
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