SKU: 83142378548

Human CFB/Complement factor B Protein, His Tag

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Description

Human CFB/Complement factor B Protein, His TagProduct Specification Species Human Synonyms C3 C5 convertase, Glycine rich beta glycoprotein (GBG), PBF2, Properdin factor B, BF, BFD Accession P00751 1 Amino Acid Sequence Protein sequence (P00751 1, Thr26 Leu764, with C His Tag)

Product Specification


Species Human
Synonyms C3/C5 convertase, Glycine-rich beta glycoprotein (GBG), PBF2, Properdin factor B, BF, BFD
Accession P00751-1
Amino Acid Sequence

Protein sequence (P00751-1, Thr26-Leu764, with C-His Tag) TPWSLARPQGSCSLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKVASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQAVYSMMSWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLGFL
Expression System HEK293
Molecular Weight Predicted MW: 84.7 kDa Observed MW: 96 kDa
Purity ＞95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Complement Factor B is a pivotal zymogen in the alternative pathway of the complement system. This serine protease circulates in plasma and is essential for innate immunity. Its activation occurs when it binds to C3b, forming the C3 convertase (C3bBb) upon cleavage by Factor D. This enzyme complex amplifies the complement response by cleaving more C3, driving opsonization, inflammation, and the formation of the membrane attack complex. Factor B also plays a role in the lectin pathway. As a key regulator, its deficiency or dysfunction is linked to susceptibility to infections and autoimmune diseases like atypical hemolytic uremic syndrome.

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SKU: 83142378548

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4.2 ★★★★★
Based on 8 reviews
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Product Reviews
J
jorban
Whiting, US
★★★★★ 4
A Simple, Affordable Cabin Filter That Does the Job
I have a mechanic I really trust, which is no small thing these days. The trade off is that he charges a little more for routine services like oil changes, and those visits always include a full vehicle inspection. To manage the cost, I make a point of handling the easy maintenance items myself so he does not feel the need to replace them with higher priced OEM parts. Cabin air filters fall squarely into that category. It takes me about two minutes to replace one, and doing it myself typically saves around fifty dollars. That was the motivation behind picking up this filter for my Toyota Sienna. Right out of the package it fit perfectly. The size is exact, which is important since cabin filters need a snug frame to work properly. There is a clear airflow direction arrow printed on the side, which is one of the two key things I always look for. Without that, it becomes guesswork and you risk installing the filter backward. With the arrow in place, installation is a quick slide and close operation. Functionally, cabin filters are hard to evaluate in real time. You do not get a dramatic change the moment you swap them out. What I rely on instead is whether they fit correctly, whether they load evenly over time and whether they avoid shedding material as they age. Based on construction and feel, this one meets those expectations. It is pleated well and the frame holds its shape. All signs point to it filtering properly, which is the baseline requirement. Because cabin filters need changing fairly often, it never makes sense to overspend on OEM versions unless you have a specific airflow sensitivity or unique environmental need. This filter costs far less and performs the key functions just as well for general use. In my Southern California environment, where dust and pollen appear regularly, I prefer to replace filters on the more frequent side, which makes the lower cost even more practical. The simplicity of the whole process is what I appreciate most. No tools, no struggle, no surprises. The filter pops in cleanly, the compartment closes and the job is done. When paired with the peace of mind of not paying dealership pricing for such a simple part, it becomes an easy product to recommend. A dependable, properly fitting cabin filter at a very reasonable price. Four stars.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 4, 2025
K
Kevin Barr
Cuba, US
★★★★★ 5
So premium I can't even test the quality
edit- after about six weeks of driving through various conditions I can say that the air quality this filter produces is excellent., removing all smoggy odor. There is a minor soapy smell that is not offensive, just unusual. So I am very pleased with this item. original review- This really seems like a premium upgrade compared to the budget filters I normally buy. Unfortunately I live in a hot and dry climate (no humidity buildup to cause musty or sour odors and AC always running which dries the air also) and I do not smoke so I never have any odor problems in my vehicle to test the charcoal feature with. I also am not prone to dust allergies so I don't know how helpful the HEPA feature is. If I get stuck in traffic in a smoggy area or behind an especially smoggy vehicle I will switch to fresh air mode to learn if the charcoal feature helps and update this review. There is no paperwork in the box or arrows printed on the filter to determine which way to insert it. I am assuming the airflow path is downward and should pass through the paper side first, so I installed the paper side up.
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Reviewed in the United States on November 9, 2025
D
D Radcliffe
Bozeman, US
★★★★★ 5
It's a fit
This was a good fit for my 2010 Camry. Way nicer than the air filter I had in there before. I don't know what all those charcoal things do but it makes me feel like my car will have better air than the rest of of life. All the packaging and labels were Chinese, so I had to take my best guess about which way the air was supposed to flow. Other than that it was pretty easy to install. Just stick it in the hole. Seems to work well, I haven't noticed any new noises. Seems like a higher end filter. Hopefully it lasts the ten years before I change it next
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Reviewed in the United States on November 9, 2025
D
D. Porrey
Lowell, US
★★★★★ 5
Very Different, But Works Well
This is built much different than the others. It has a foam seal around the edges. The filter portion is standard, but the carbon activated material is a setoff beads suspended between a screen a honeycomb structure. There is air freshener built-in to help with the smell in the car. Fits well in my 2015 RAV4. Just as easy to install as any other filter. The price is on the high side so with this one I am hoping to get at least one year of use from it.
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Reviewed in the United States on November 25, 2025
P
Placeholder
Boise, US
★★★★★ 4
Well-Made Carbon Cabin FIlter
I love the honeycomb carbon filter on this cabin filter. It looks like it will do an excellent job cleaning the air in my car. It came in a cardboard box and was easy to install and fit my Toyota well. I would have appreciated some arrows on it, like other filters come with, to let me know I was inserting it correctly. I just followed the example of the one already in my car. If you accidentally take that one out first, you may not remember which side goes where. So, my improvement would be arrows on the filter itself. Otherwise, the airflow seems great, it functions well and seems to be a great quality!
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Reviewed in the United States on November 14, 2025

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