SKU: 94459427711

IL-31 Protein, Human

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Description

IL-31 Protein, HumanProduct Specification Species Human Synonyms IL 31,IL31,Interleukin 31 Accession Q6EBC2 Amino Acid Sequence Ser24 Thr164 Expression System E. coli Molecular Weight 16kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM PB, 100mM NaCl, pH6. 5 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.

Product Specification


Species Human
Synonyms IL-31,IL31,Interleukin-31
Accession Q6EBC2
Amino Acid Sequence Ser24-Thr164
Expression System E.coli
Molecular Weight 16kDa (Reducing)
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM PB, 100mM NaCl, pH6.5
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.J Allergy Clin Immunol. 2023 Jul 13;S0091-6749(23)00888-6. Online ahead of print.
2. Allergy. 2023 Jul 13. Online ahead of print.
3. Clin Exp Med. 2023 Jul 1. Online ahead of prin

Background

IL-31 which produced by activated Th2-type T cells. IL-31 signals through a receptor composed of IL-31 receptor A and oncostatin M receptor. IL-31 activates STAT3 and possibly STAT1 and STAT5 through the IL-31 heterodimeric receptor composed of IL31RA and OSMR. IL-31 has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. Patients with atopic dermatitis, chronic spontaneous urticaria, allergic contact dermatitis, prurigo nodularis, primary cutaneous lymphoma and mastocytosis exhibit increased serum levels of IL-31 protein and elevated IL-31 mRNA in the skin.

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SKU: 94459427711

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Adorable123
Pawtucket, US
★★★★★ 5
Worth pvery penny!!
Format: Paperback
I love this book so much because it has rationales!!!, which are very important in knowing why you got a question wrong or right. There are practice questions that helped me a lot as well. I passed my peds exam because of this book, so if you are a NEW nursing student or one about to take a peds class make sure you get this book and practice after every lecture.
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Reviewed in the United States on December 30, 2022
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Peachyki 💗
Natrona Heights, US
★★★★★ 5
Used this a lot!
Format: Paperback
This was a Peds staple for my RN bridge program! Book helped me out a lot! Read those rationales! They are amazing!
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Reviewed in the United States on August 6, 2023
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Andrea Wu
Boise, US
★★★★★ 5
Great
Format: Paperback
Practice questions are great and the rationals are easy to understand. Overall a pretty good investment.
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Reviewed in the United States on March 21, 2023
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So beautiful
Bozeman, US
★★★★★ 5
Good for extra practice questions
Format: Paperback
Nursing students must have
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Reviewed in the United States on December 26, 2022
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K.Z.
Grantham, US
★★★★★ 3
Numerous Errors!
Format: Paperback
They need to review the text and circulate a revised edition with a page listing errors noted since publication. Find another source to practice with.
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Reviewed in the United States on October 19, 2023

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