SKU: 34143342339

Nano DeBEE High Pressure Homogenizer

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Description

Nano DeBEE High Pressure HomogenizerOverview The BEE Nano DeBEE has the highest processing energy of any electric benchtop high pressure homogenizer. The laboratory scale Nano DeBEE allows users to easily adjust a wide variety of parameters to ensure the optimum process for excellent homogenization. Pressure, flow and process duration are all independently controlled, and the BEEI homogenizing cell is the only high pressure homogenization technology that allows for control of process

Overview

The BEE Nano DeBEE has the highest processing energy of any electric benchtop high-pressure homogenizer.  The laboratory scale Nano DeBEE allows users to easily adjust a wide variety of parameters to ensure the optimum process for excellent homogenization.  Pressure, flow and process duration are all independently controlled, and the BEEI homogenizing cell is the only high pressure homogenization technology that allows for control of process duration.  Likewise, the amount of cavitation, shear, and impact the sample is exposed to can be adjusted by varying the aforementioned control parameters and by changing the configuration of the Emulsifying Cell..

 

The user-friendly Nano DeBEE is suitable for a wide range of applications, including cell disruption, emulsification, dispersions, and particle size reduction. The core technology - BEEI's proprietary homogenizing cell - ensures excellent results in fewer passes.

Nano DeBEE homogenizers are extremely flexible. They can be configured for parallel flow (high cavitation, low shear, low impact), reverse flow (maximum shear, cavitation, and impact), short or long process times, and a variety of processing nozzle sizes and reactors.  It has a built-in product cooling heat exchanger and is suitable for applications utilizing back pressure and a wide range of volumes.

Features:

  • Easy cleaning and maintenance
  • Suitable for sanitary applications
  • Low to high operating pressure. Up to 45,000 PSI / 3100 bar for maximum experimentation
  • Scalable to manufacturing
  • Product cooling heat exchanger (optional)
  • Adjustable back-pressure
  • Sample size as small as 15 ml
  • Lifetime training for new employees and students
  • Best-in-class 2-year warranty!

The Nano DeBEE High-Pressure Laboratory Homogenizer is available in the following models:

Model HP Max. Operating
Pressure
Capacity
(ml / min) / (l / hr) / (gal / hr)
Lead Time
Nano DeBEE 45-2 1 45,000 psi
3,100 bar
35 / 2 / 0.8 2 - 4 weeks
Nano DeBEE 30-4 2 30,000 psi
2,000 bar
70 / 4 / 1 2 - 4 weeks
Nano DeBEE 45-6 Gen II 2 45,000 psi
3,100 bar
115/ 6 / 1.85 2 - 4 weeks

The Nano DeBEE high-pressure homogenizing system combines the homogenizing forces of most other homogenizers into a single instrument:

  1. Before passing through the nozzle, a turbulent flow may be created to vigorously premix the product (like stirrers and agitators).
  2. A large pressure drop upon exiting the nozzle causes cavitation (like ultrasonic homogenizers).
  3. The product, which is travelling fast enough to cut metal, then impacts the end fixture in the Emulsifying Cell, creating a strong physical force (like bead mills).
  4. Shear forces are present throughout the Emulsifying Cell due to changes in relative velocity in the moving liquid.  These shear forces are higher than in rotor-stator homogenizers.

All of the above forces may be adjusted in the Nano DeBEE, allowing for highly customized operation in order to achieve the desired particle size in a highly reproducible manner with minimal passes and processing time.

Key Attributes
Homogenizer Type High Pressure
Sample Throughput 1 Sample
Sample Volume (min) 12 ml
Sample Volume (max) 2 or 4 l / hr (model dependent)
Usage / Placement Benchtop
Cooling May be required
Warranty 1 years
Noise Level 65 db
Weight 68 lbs
Width 36"
Depth 22"
Height 18"
Manufacturer Specifications

110V or 220V power supply, single phase
Quiet operation, below 65 dBA

FAQ

This is a big decision. Can we try a Nano DeBEE before we purchase it?

Yes, for a fee. If your samples are in no way hazardous Nano DeBEE can test and optimize your high-pressure homogenization process for you, provide an on-site demo, or you can lease a unit for one to two months. If you're interested in any of those options, shoot us an email or give us a call and we'll be happy to discuss costs and help set it up.

 

What is the maximum viscosity substance that the Nano DeBEE can handle?

Very high. Well over 20,000 cps. The rule of thumb with the Nano DeBEE is that if it's liquid and you can pump it, you can homogenize it in the Nano DeBEE. At very high viscosities, however, you may need to use air pressure to feed the sample into the machine.

If we had to draw a line, it would be at 100,000 cps.

 

What is the procedure for cleaning or sterilizing the Nano DeBEE?

Most users simply run a suitable solvent through the system. Done properly, this is generally satisfactory to meet regulations pertaining to the sterilization of instrumentation (FDA, etc.).

 

What kind of cooling is required for the heat exchanger?

The heat exchanger requires a stream of cold liquid. This can be done by feeding it cold tap water, or a recirculating chiller can be used. BEEI recommends a chiller with approximately 1750 watts of cooling capacity.

 

Can the Nano DeBEE be used for continuous applications?

The Nano DeBEE is intended for small-scale processing or R&D applications and is not designed with continuous use in mind. While you theoretically can use the Nano DeBEE 24/7, it would be analogous to buying a car and driving it 100k miles / year. In situations where you would be running it for over 4 hours / day, we would suggest scaling up to a larger system designed for continuous use.

BEEI does have larger-scale systems that can be used 24/7. The Micro DeBEE is one such option, but there are other, larger scale systems as well. If you would be interested in learning more, please contact us.

 

I am trying to homogenize gas into a liquid. Would the Nano DeBEE be suitable for my application?

No. Products which may contain significant amounts of gas should be degassed before homogenization in the Nano DeBEE. Gas bubbles in the feed fluid implode when pressure is generated, which creates water-hammer effect or extreme pressure spikes that are detrimental to the equipment.

 

Is the Nano DeBEE explosion proof / is it suitable for C1D1 or C1D2 environments?

No, the Nano DeBEE is not explosion proof. If you are looking for a high-pressure homogenizer which can be used in hazardous environments, the air-powered Micro DeBEE may be suitable as it does not have any electronic components.

 

What safety features are there on the Nano DeBEE to mitigate the inherent risks of high pressure systems?

  • On the hydraulic side there is pressure relief valve
  • On the process side, specifically on the medium pressure section , there is a relief valve on the back pressure area
  • On the high pressure side there are weep holes to release pressure if there is a leak in the system
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 34143342339

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Ariel
Birmingham, US
★★★★★ 3
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3 stars Thank you Netgalley and Briar Boleyn for the ARC! A camelot/king Arthur retelling with fae. I was hooked by the idea of this book immediately and was eager to jump into this world. • slow burn • enemies to lovers • who did this to you Morgan Pendragon watched her mother die by her father's hand when she was just eight years old, hiding under the bed. Morgan is believed to have the tainted blood of the fae in her veins and is cast aside so that her fathers illegitimate son, Arthur, can become the king. She's seen his cruel treatment of the fae firsthand, so when he sends her on a journey to find a fae weapon she seizes the opportunity to do more with her life. Along the way, she finds more than she could have imagined. I don't know a whole lot about King Arthur and Camelot but I had a lot of fun with this story! The plot has some similar tropes to popular romantasy books (From blood and ash) but there's enough originality here that it doesn't feel like I'm reading a copy. I liked how the fae were different in appearance than what is typical in most fantasy books I've read. In this book they have blue hair, violet skin and a wide range of other characteristics. I thought that the world building was easy to follow and I could easily immerse myself into this world. After reading the blurb I kept wondering when she was going to go on the journey to find Excalibur and it doesn't happen until around the 45% mark. The story is a bit slow at times but starts to pick up once they begin their journey to find Excalibur. The John Wick style Inn was a fun concept that I enjoyed reading about. There are a lot of similarities to this and FBAA and I would have liked to have it be a little more different, but I'm hoping book two will have the story turn into something of its own. Overall I enjoyed reading this story and I'm looking forward to reading book two especially after that ending.
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Reviewed in the United States on May 27, 2023
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Whiting, US
★★★★★ 5
Good start to a series
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I delayed reading the series for reasons I don’t remember. But my TBR list is huge so I thought I’d take a shot of this and I was pleasantly surprised. I didn’t think the blurb about it was anything special. But it was a very good book. It took some interesting twists and turns. I am so glad the second book is already out. Because I would not have waited patiently. Very slow burn but good storyline. 🔥🔥/5
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Reviewed in the United States on January 3, 2025
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Jammie Clark
Massapequa, US
★★★★★ 4
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Multiple points of view. 3 Alpha men and an Omega male. She is a Beta in training for a new program placing betas in Alpha/Omega packs. Mila is only doing the program for the money to take care of her dad. She wasn't expecting to fall for a pack but when she sees this packs Omega she is done for. There is just something about him. His Alphas are good looking as well. Too bad she is hiding a secret and their government is acting shady. I liked it and can't wait to see where their story goes.
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Bri Hires
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I love this type of story. And omegaverse is one of my all time favorite genres. But there are a few things that pulled me out of my enjoyment while I was reading. It was repetitive at times as well as struggled with telling not showing. So we didn’t always feel like we were experiencing things with the main character. There were also some plot holes but they may still be answered in part 2. Now this isn’t to be said I didn’t enjoy parts of the story. I loved the almost instant love between Mila and Oliver. And how he started changing around her.
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Kimberly G
Lexington, US
★★★★★ 5
delightful read
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What a delightful read. The characters are awesome, the plot was so good, I loved it. I was intrigued and it kept me wanting more. Told in multiple pov, the book sucks you in and doesn’t let go. I cannot wait to read the next book.
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