SKU: 42444858519

Rapid Reset Multi-Senolytic - 30 capsules

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Description

Rapid Reset Multi-Senolytic - 30 capsulesTotal Body Reset: Powered by 15 Senolytic Compounds* Helps eliminate zombie senescent cells*1 9 Promotes youthful, high functioning cells*1 8,10 Helps maintain a healthy inflammatory response*7,8,11 16 Supports total body tissue rejuvenation*7,12,17,18 Strategic 3 day protocolmodeled after leading senolytic research*1,5,14,19 View Certificate of Analysis A Broader, Deeper Cellular Cleanse* As we age, zombie senescent cells accumulate throughout the

Total-Body Reset: Powered by 15 Senolytic Compounds*

  • Helps eliminate “zombie” senescent cells*1-9
  • Promotes youthful, high-functioning cells*1-8,10
  • Helps maintain a healthy inflammatory response*7,8,11-16
  • Supports total-body tissue rejuvenation*7,12,17,18
  • Strategic 3-day protocol—modeled after leading senolytic research*1,5,14,19

View Certificate of Analysis

A Broader, Deeper Cellular Cleanse*

As we age, “zombie” senescent cells accumulate throughout the body—releasing pro-inflammatory signals that impair cellular function, accelerate aging, and compromise tissue health. While individual compounds like quercetin and fisetin show individual promise, emerging research suggests that multi-senolytic strategies—combining multiple ingredients that act through complementary pathways—may offer a broader and more effective approach to clearing senescent cells across multiple tissues.*1-9

Rapid Reset Multi Senolytic delivers a powerful combination of 15 senolytic ingredients in a doctor-formulated 3-day protocol. Designed to activate the body’s natural clearance and renewal mechanisms, this high-intensity, low-frequency regimen is designed to spark the body’s natural senolytic mechanisms—promoting head-to-toe rejuvenation. Whether you're new to senolytics or upgrading your monthly longevity routine, this is ProHealth’s most comprehensive cellular reset yet.*1-10,12,14-19

What Makes Ours Better?

  • Multi-Ingredient Strategy: Combines 15 carefully selected ingredients—each chosen for its unique senolytic potential—to target aging cells through complementary mechanisms.*1-9,12,15-18
  • Ultra-Pure Sourcing: Uses high-quality, research-backed ingredients for purity, consistency, and results you can trust.*
  • Advanced Absorption Technology: Features next-gen delivery systems like FenuMat® quercetin, liposomal resveratrol, and turmeric phytosome for enhanced bioavailability where it counts.*20
  • Clinically Researched Compounds: Includes well-studied senolytics like fisetin and quercetin, plus Senactiv®—a patented ingredient shown in human studies to reduce senescent cells in exercising skeletal muscle.*1-9,12,15-18
  • 3-Day Protocol: Built on the “hit-and-run” senolytic model, this short-duration strategy is designed to selectively clear senescent cells while minimizing effects on healthy tissue.*1,5,14,19

The ProHealth Difference

  • Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
  • Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
  • Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle. 
  • Manufactured in the USA: Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.

The Ultimate Weapon Against Zombie Cells*

As cells age or become damaged, they can enter a state called senescence—where they stop dividing but don’t die. Instead, they linger in the body as so-called “zombie cells,” releasing a mix of compounds known as SASP (Senescence-Associated Secretory Phenotype), which can influence surrounding cells and affect normal tissue function. Over time, senescent cells tend to build up in areas like the joints, skin, lungs, blood vessels, and fat tissue—contributing to many of the visible and invisible effects of aging.

Why Senolytics Matter

Senolytics are a class of compounds that support the body’s ability to target and clear dysfunctional cells, promoting cellular balance and healthy tissue renewal.*1-10 However, there’s a challenge: not all senescent cells are the same. These cells can vary in several ways:

  • Resistance to clearance
  • Location of accumulation in the body
  • Signaling molecules they release

Due to this variability, while single-ingredient senolytics can offer targeted support, a multi-senolytic strategy is more effective. It casts a broader net, helping to address diverse senescent cell populations across multiple tissues and cell types.*1-3,5-8,10

Introducing: The 3-Day Rapid Reset Protocol

This science-backed protocol uses short bursts of high-intensity senolytic activity—also known as a “hit-and-run” strategy—to help clear lingering senescent cells and support full-body cellular renewal.*1-9,12,14,17,19,28

How to Use:

  • Take ten (10) capsules daily for 3 consecutive days
  • Discontinue use on day 4
  • Wait 4–6 weeks before repeating the cycle

This intermittent approach is designed to deliver meaningful results in a compact timeframe—without the need for continuous supplementation.*1,5,14,19

For ongoing cellular support between senolytic cycles, daily antioxidant compounds like Quercetin or Fisetin can help maintain a healthy internal environment.*1-7

A Word from our Chief Science Officer

“Clearing senescent cells is one of the most promising frontiers in longevity science. While single-agent protocols are a good starting point, aging is complex, and senescent cells behave differently depending on the tissue and the signals involved. That’s why our Rapid Reset Multi Senolytic takes a broader, more comprehensive approach, combining 15 potent compounds into an easy-to-follow 3-day protocol. This is a new benchmark in senolytic support.”

Ingredient Highlights

  • Senactiv®: A proprietary blend of extracts from Panax notoginseng and Rosa roxburghii, clinically shown to help reduce senescent cells in muscle.*
  • Fisetin: A polyphenol found in fruits like strawberries and apples, shown in studies to be one of the most potent senolytic agents available today.*
  • Quercetin: Often combined with other compounds, this flavonoid has been studied for its role in promoting the removal of senescent cells and improving age-related conditions.*
  • Trans-Resveratrol: A polyphenol commonly found in red grapes, known for activating longevity-associated sirtuins and supporting heart and brain health.*
  • Curcuminoids: A group of yellow pigments extracted from turmeric root, commonly used to support a healthy inflammatory response.*
  • Citrus Peel Blend: Powerful polyphenols derived from citrus fruits, recognized for supporting healthy blood vessels and combating free radicals.*
  • Phycocyanin: A blue pigment derived from blue-green algae, valued for its antioxidant properties and ability to support cellular health.*
  • Theaflavins: Unique polyphenols formed during the fermentation process of black tea, when catechins (the primary antioxidants in green tea) are converted into theaflavins.
  • EGCG: One of the most active and studied types of catechins in green tea, known for boosting metabolism and protecting cells from oxidative stress.*
  • Apigenin: A flavonoid commonly found in parsley, chamomile, and celery, shown to target the CD38 enzyme and support healthy NAD+ levels.*
  • Rutin: A bioflavonoid related to quercetin, known for its strong antioxidant properties and its key role in supporting vascular health.*

Pioneering Health and Wellness Products Since 1988

For nearly four decades, ProHealth has been dedicated to crafting the world's highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do.

References:

    1. Mahoney SA et al. Aging Cell. 2024;23(3):e14060.
    2. Yousefzadeh MJ et al. 2018;36:18-28.
    3. Zhao R et al. PeerJ. 2023;11:e16463.
    4. De Sousa Lages A et al. Int J Mol Sci. 2022;23(17):9957.
    5. Lorenzo EC et al. Front Aging. 2023;4:1161799.
    6. Tavenier J et al. Mech Ageing Dev. 2024;222:111995.
    7. Deledda A et al. Int J Mol Sci. 2022;23(24):16219.
    8. Wiciński M et al. Nutrients. 2023;15(16):3578.
    9. Zhu Y et al. Aging Cell. 2015;14(4):644-658.
    10. Zheng LT et al. Int Immunopharmacol. 2008;8(3):484-494.
    11. Dias E, Poojary DD. 2024;6(3).
    12. Mbara KC et al. Pharm Med. 2022;36(6):331-352.
    13. Khan N et al. Antioxid Redox Signal. 2013;19(2):151-162.
    14. Sun Y et al. Life Med. 2022;1(2):103-119.
    15. Della Vedova L et al. Pharmaceuticals. 2025;18(2):138
    16. Pirmoradi S et al. Drug Res. 2018;68(04):213-221.
    17. Wu J et al. J Ginseng Res. 2019;43(4):580-588.
    18. Sohn EJ et al. Am J Chin Med. 2018;46(04):853-873.
    19. Hickson LJ et al. EBioMedicine. 2019;47:446-456.
    20. Joseph A et al. ACS Omega. 2022;7(50):46825-46832.
Supplement Facts
Serving Size: 10 Capsules
Servings Per Container: 3
Amount Per Serving %DV
Fisetin (from Rhus succedanea Stem Extract) 1,500 mg
Fenumat® Quercetin Complex (from Sophora japonica Flower Buds, Fenugreek Seeds, Sunflower Lecithin) 1,000 mg
Veri-te® Trans-Resveratrol 500 mg
Meriva® Turmeric Phytosome™ (Curcuma longa Root Extract/Phospholipid Complex from Sunflower) 500 mg
Citrus Peel Blend
Hesperidin, Naringin, Tangeretin, Nobiletin
400 mg
Phycocyanin (from Blue Spirulina (Arthrospira platensis) Whole Algae Extract) 300 mg
Theaflavins (from Black Tea Leaf Extract) 275 mg
EGCG (from Green Tea Leaf Extract) 200 mg
Apigenin (from Apium graveolens Seed Extract) 150 mg
Rutin (from Sophora japonica Flower Buds) 100 mg
Senactiv® (Panax notoginseng Root Extract, Rosa roxburghii Fruit Extract) 50 mg
† Daily Value (DV) not established.

FenuMat® is a registered trademark of Akay USA, LLC, an Oterra company. Veri-te® is a registered trademark of the Lallemand group. Meriva® and Phytosome™ are trademarks owned by Indena S.p.A., Italy. Senactiv® is a registered trademark of NuLiv Science USA Inc.

REV.05.25

  • OTHER INGREDIENTS: Cellulose (capsule), rice flour.
  • SUGGESTED DAILY USE: Take ten (10) capsules per day on 3 consecutive days. Wait 4 weeks before repeating. Use monthly for best results.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
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Exchange/Return Notes
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james maher
Waukegan, US
★★★★★ 5
My Denon ROCKS
Style: AVR-X3800H
Pros: Nine Amps power a 9.1 or 7.1.2 or 5.2.4 speaker configuration because most of us want Atmos to work in our listening room. Plenty of power available in each amp and each configuration Atmos DTS IMAX plus any other codec or audio visual enhancement is available. Yes, 4K 8K HDR all supported. Three HDMI outputs Preamp output for up to 11 channels so any combination of preamp vs. power amplifier output is available. But not both preamp AND power amp for the same channel. And you can pick and choose which channel you want for pre amp vs power amp individually. So it can function as a AV Preamp Processor at very reasonable price point. DAC (changes Digital Signal to Analog) with all the power amplifiers you could want. High quality, including DSD, is an added bonus. Setup customizable to the nth degree. Some people might say too many options but that’s the way we get this AVR to meet our individual requirements I’ve been working with the setup for the last week and have dialed in for my needs. Still playing with the HEOS but I think it’s working well for now. Various HDMI inputs need different surround settings, I like the DTS best, but the unit has a way to include default settings for each HDMI. I’ll use default settings with my BluRay. And I’ll use direct or pure or whatever the source allows for music and streaming. And most users will want a streaming stick like the Amazon one otherwise you can’t get the Atmos signal to work. Older streamers won’t pass the Atmos signal though. The only problem with a device like this is you will buy more speakers and amps and possibly even more subwoofers, the unit will support 4 subwoofers. Enjoy So I will get back to you with comments about longer term issues. BTW the 3800 was a refurbished version for $999 . Definitely an excellent value. The online reviews are quite favorable. Even the audiophiles are still learning the nuances of setup. It’s worth the extra effort to get the most out of each user’s individual existing equipment. Cons: None. I’ve been an audio video nerd for decades so I can say that the setup effort is easily justified once the user, with user manual in hand, patiently works out the desired configuration. The audio expert online information is invaluable. I have 21MBS broadband service in my region. Even with this limitation I have more than enough added capacity with the Denon that I would never return it to seller unless someone catastrophic happened. Yes I like it that much.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 1, 2024
T
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Tim J.
Pawtucket, US
★★★★★ 5
Denon Refurb AVR-X3800h.. IMPRESSIVE!
Style: AVR-X3800H, Style: AVR-X3800H
I did a lot of homework and made contact with the seller. Great communication. Turns out all of the Denon refurbished receivers are inspected or repaired by DENON, and re-certified only after passing tests upon functional as new. It arrived in a Denon box, very well insulated. Contained all NEW accessories like new & sealed. Appears flawless. The setup was easy since I have years of previous experience with surround systems. This replaced my Onkyo of 10 years. And WOW, the difference is phenomenal! Great onscreen setup + smart phone app makes it nice for making fine tuning adjustments. This model is packed with all the latest tech. The Durac Live is easily downloadable, but I am so impressed with the Audacy setup I didn’t buy the download. Great value refurbished. It comes with a one year warranty, so I purchased the 3 year assurion warranty since I saved so much money. Very happy.
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Reviewed in the United States on February 18, 2024
C
Verified Purchase
cqlink
Massapequa, US
★★★★★ 1
PITA to Set-Up and Hard to Connect to WiFi
Style: AVR-X3800H
This one went right back after hours spent on set-up. Room correction software was buggy as well. I couldn't get it going and called it a day and bought the Onkyo TX-RZ50 which is equally hard to get consistent sound and and hard to cnnect to WiFi and Bluetooth. Onkyo support, however, is far superior.
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Reviewed in the United States on September 28, 2024
K
Verified Purchase
Kberkel
Boise, US
★★★★★ 5
Great receiver, Digital Room Correction is worth it
Style: AVR-X3800H
Being a refurb, the unit seems brand new. No issues at all, working great so far after months of use. Audyssey XT32 works really well in my main seating position. Any other listening position on the couch is not great, but not the receivers issue. Just noting that there’s only so much you can fix with digital room correction, my room is the opposite of ideal. Love the multiple sub control. Dynamic EQ is fantastic also. Audyssey transformed my music. My 5.2 speaker setup is Frankenstein’d together with different brands and it was interesting to see the drastically different frequency responses of each speaker. With it all tuned, it sounds great. I find myself just sitting down and jamming to music for hours.
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Reviewed in the United States on January 8, 2024
S
Verified Purchase
Sinatra2002
Alexandria, US
★★★★★ 5
Solid!
Style: AVR-X3800H
It's a rock-solid receiver with modern and future-proof features. Denon isn't the flashiest or most aesthetically pleasing design; however, the unit is reliable and sounds great. I used Dirac Live to fine tune the system, and it's been a worthwhile upgrade from my X-2700. 
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Reviewed in the United States on July 15, 2025

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