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Description
Cycloastragenol - 10 mg, 30 capsulesCycloastragenol is a bioactive molecule derived from Astragalus, a botanical widely used in Traditional Chinese Medicine and prized for its adaptogenic, immune supporting, and whole body benefits. Emerging evidence suggests cycloastragenol may unlock key aspects of healthy aging; it is known to support: Telomerase activation* Healthy telomere length* Healthy DNA structure* Antioxidant activity* Optimized aging at the genetic level* View Certificate of
Cycloastragenol is a bioactive molecule derived from Astragalus, a botanical widely used in Traditional Chinese Medicine and prized for its adaptogenic, immune-supporting, and whole-body benefits. Emerging evidence suggests cycloastragenol may unlock key aspects of healthy aging; it is known to support:
- Telomerase activation*
- Healthy telomere length*
- Healthy DNA structure*
- Antioxidant activity*
- Optimized aging at the genetic level*
Research-Supported Benefits:
Supports telomere length and healthy aging. Telomere attrition is one of the hallmarks of aging. Telomeres are the protective caps of chromosomes and help protect them from degradation. Critically short telomeres have been associated with cellular senescence and other parts of the aging process. Cycloastragenol may help activate telomerase, the major enzyme responsible for maintaining telomere length.*Supports healthy cell cleanup and antioxidative status. Improvement in markers related to antioxidative status was observed in the presence of cycloastragenol in an animal study. Cycloastragenol was also shown to help support the elimination of senescent cells in another animal study.*
References:
Ikram M, Jo MH, Choe K, et al. Cells. 2021;10(10):2719.
Ip FCF, Ng YP, An HJ, et al. Neurosignals. 2014;22(1):52-63.
Zhang Y, Gao D, Yuan Y, et al. Int J Mol Sci. 2023;24(7):6554.
- May help activate telomerase, the major enzyme involved in adding back telomeric DNA to the ends of chromosomes, by regulating MAPK and Akt signaling pathways.*
- May help support cAMP response element binding (CREB) activation.* CREB helps regulate gene expression related to cell survival and replication in many cell types.
- May support antioxidant activity in the aging brain.*
| Supplement Facts | ||
|---|---|---|
| Serving Size: 1 Capsule |
||
| Servings Per Container: 30 |
||
| Amount Per Serving | %DV | |
| Cycloastragenol (from Astragalus membranaceus Extract) (root) |
10 mg | † |
| † Daily Value not established | ||
REV.06.24
- OTHER INGREDIENTS: Vegetable capsule, rice flour.
- DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, fish, shellfish, tree nuts, peanuts, sesame.
- SUGGESTED DAILY USE: Take one (1) capsule per day, or as directed by your healthcare professional.
-
NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper evident seal is broken or missing. KEEP OUT OF REACH OF CHILDREN.
-
CAUTION: Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
- Superior Absorption and Bioavailability. A pharmacokinetic study showed that cycloastragenol has superior absorption and bioavailability compared to astragaloside IV, the main active constituent in A. membranaceus. This is in part due to cycloastragenol's low molecular weight.
- Science-First Formulations: We source only the highest quality ingredients backed by validated research to help you achieve your longevity goals.
- Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
- Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.5 ★★★★★
Based on 19 reviews
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Product Reviews
★★★★★ 4
I like this brush
Style: Medium Dog, Size: 1 Count (Pack of 1)
I'd used the thumb brush, the slanted brush and a human soft-bristled toothbrush on my dog over the course of four years. I hate those thumb silicone brushes because my fingers are slim so it slides everywhere. The slanted one is cool. But I got so used to being able to use this collection of human soft-bristled toothbrushes that I'd gotten from the dentist. This one felt weird at first. My dog didn't really understand what I was putting in her mouth and jerked back. We'd gotten a system down for how far back to go so I wasn't knocking her gums and held her jaw out to see her teeth. It's weird not having to do that anymore. I like the brush now. It's a little pricier than other dog toothbrushes. I think if I hadn't used human toothbrushes (and gotten so many compliments from dog vets who didn't know that was what I was using), I would've started off with this one. I'll probably use it again after the three months. Not sure yet.
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Reviewed in the United States on July 16, 2025
★★★★★ 5
Low cost buy to put off big costs later
Style: Big Dog, Size: 1 Count (Pack of 1)
These came recommended to us by our veterinary dentist. The bristles are soft and hold up great even with daily use on multiple dogs (they each now have their own toothbrush).
It definitely doesn’t beat a yearly cleaning, but it helps prevent oral issues.
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Reviewed in the United States on August 25, 2025
★★★★★ 5
The best toothbrush, and I've tried them all!
Style: Small Dog, Size: 1 Count (Pack of 1)
I have a little 4 year old Maltese and Shih Tzu mix. She has very tiny teeth that are already starting to show signs of dental disease. I know it's important that they get brushed because small breed dogs are more prone to dental and gum problems. But I've tried every little toothbrush out there and it's a battle trying to brush her teeth. And unfortunately she usually wins! This brush is the best. It is soft and round and she completely tolerates it. I put a little doggie toothpaste on it, which she likes the taste of, and I'm finally able to at least move the brush and paste around her gum line. She still fights me a bit, but nothing like she used to. I would highly suggest that you give this toothbrush a try.
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Reviewed in the United States on May 16, 2023
★★★★★ 1
Flimsy and snapped easily
Style: Big Dog, Size: 1 Count (Pack of 1)
Snapped in literally under a minute of using it. The toothbrush head is so small and the handle is really thin and flimsy even though it’s advertised for large dogs… I’m so disappointed.
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Reviewed in the United States on November 18, 2025
★★★★★ 3
does the job
Style: Medium Dog, Size: 1 Count (Pack of 1)
Its does the job of cleaning my dachshunds teeth. The only issue is that the SMALL and MEDIUM are the same size. Small was okay but wanted something that would cover more area. Picked up the Medium and they are basicly if not the same size....
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 19, 2022
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